Edward R. Biehl

Research Interests

• Organic, medicinal
• Organic synthesis of pharmacologically-active compounds
• Perhalogenated compounds

Selected Publications

1. Shashidhar Kumar Akubathini and Ed Biehl, "Copper-catalyzed Ikyne-aryne coupling reaction under microwave conditions: preparation of unsymmetric and symmetric di-substituted alkynes" Tetrahedron Lett. 2009, 50, 1809-1811.
2. Afsha Rais, Haribabu Ankati and Ed Biehl, "Microwave Assisted Synthesis of Benzoisothiazoles and Benzoisoselenazoles," Trends Heterocyclic Chem. 2009, In press.
3. Afsha Rais, Haribaby Ankati and Ed Biehl, "Preparation of 5-Nitro-2-amino[b] thiophenes and 1-(2-Amino-5-nitrophenyl) ethanones via Microwave Irradiation". J. Heterocyclic Chem. 2009, On line.
4. Lulu Wang, Michael Balderamos, Haribabu Ankati, Shashidhar Kumar Akubathini, Chelsey A. Storey, Anish V. Patel, Edward R. Biehl, Santosh R. D'Mello "1,4-Benzoxazine compounds as novel neuroprotective agents" Exp. Bio Med. 2009, In press.
5. Haribabu Ankati and Ed Biehl "Microwave-Assisted Aryne-Click Chemistry: Preparation of Benzo[d] 1,2,3]triazoles" Tetrahedrhon Lett. 2009, In press.
6. Haribabu Ankati, Shashidhar Kumar Akubathini, Santosh R. D'Mello and Edward R. Biehl "Synthesis of 2-Benzylidene and 2-Hetarylmethyl Derivatives of 2H-1, 4-Benzoxazin-3-(4H)-ones as Neuroprotecting Agents" Synth. Commun. 2009, In press.
7. Haribabu Ankati, Shashidhar Kumar Akubathini, Sukanta Kamila, Chandrani Mukherjee, Santosh R. D.Mello and Edward R. Biehl "Synthesis of 3-Benzylidene, 5-Substituted 3 Benzylidene, 3-Hetarylmethylene and 5-substituted derivatives of Indolin-2-ones" Open J. Org. Chem. 2009, 3, 1-10.
8. Haribabu, Yan Yang, Dunmin Zhu, Edward R. Biehl and Ling Hua, Synthesis of Optically Pure 2-Acido-1-arylethanols with Isolated Enzymes and Conversion to Triazole-Containing b-Blocker Anallgues Employing Click Chemistry" J. Org. Chem. 2008, 73, 6433-6436.
9. Michael Balderamos, Haribabu Ankati, Shashidhar Kumar Akubathini, Anish V. Patel, Sukanta Kamila, Chandrani Mukherjee, Lula Wang, Edward R. Biehl and Santosh R. D'Mello, "Synthesis and Structure-Activity Relationship Studies of 3-Substituted Indolin-2-ones as Effective Neuroprotective Agents" Exp. Bio. & Medicine 2009, 233, 1395-1402.
10. Hongming Zhang, Haribabu Ankati, Shashidhar Kumar Akubathini and Ed Biehl "(Z)-5-Fluoro-3-[1H-pyrrol-2-yl)-methylene}-Indolin-2-one" Acta Cyrst. 2009, E65, 08.
11. Hongming Zhang, Haribabu Ankati, Shashidhar Kumar Akubathini and Ed Biehl, "(E)-5-Chloro-3-(2,6-dichlorobenzylidene)-Indolin-2-one" Acta Cryst. 2008, E64, o2103.
12. Hongming Zhang, Haribabu Ankati, Shashidhar Kumar Akubathini and Ed Biehl, (Z)-3-Phenylallylidene]indolin-2-one, Acta Cryst. 2009, E65, o363.

Courses Taught

• Organic Chemistry (CHEM 3371/2)
• Organic Chemistry Laboratory (CHEM 3117/8)
• Advanced Organic Chemistry (CHEM 5393)