Notes
Outline
STDs@SMU
Nancy Merrill, MD
Peter F. Davis, MD
SMU Student Health Center
STD Risk Factors
Sexual activity
Early age of sexual initiation
Increased number of partners
Use of drugs or alcohol
Belief in invulnerability--”It doesn’t happen to people like me”
Genital Warts
Caused by Human Papilloma Virus (HPV)
Sexually active persons who have had > 3 partners or whose partners have had > 3 partners  have a 75 % chance of being infected with virus.
Over 80% of sexually active students will contract and transmit HPV by the time they graduate from college.
Intercourse vs.. Outercourse
“Rub a dub dub”
Penile – Vaginal penetration is not required to contract HPV.
Genital contact or hand/oral manipulation may result in  HPV infection.
“Virgins” (no vaginal penetration by penis) can and do still contract HPV.
Facts (aka Bad News)
Minimal symptoms
Low risk strains cause genital warts
High risk strains (oncogenic=cancer causing) usually have no symptoms
Cancer is only detected by Pap or biopsy
Most often transmitted without visible warts
SMOKING greatly increases progression to cervical cancer!!!
Good (?) News
Most (70%) of all HPV infections will disappear in an immunocompetent (healthy) non-smoker without any treatment within 12 to 24 months!
2 pharmaceutical companies are now applying for FDA approval for HPV vaccines!
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Genital Warts
  Diagnosis and Treatment
Physical exam, Pap smear, HPV DNA typing from Pap (or rectal swab from rectal penetration) or colposcopy
Topical therapy, freezing, laser ablation, LEEP
Condoms and spermicides decrease transmission
Treatment of abnormal (pre-cancerous) cervical cells can aid cancer prevention.
Herpes Simplex Virus (HSV)
Prevalent among college students
Type 1 - Oral  (Freshmen: 37%       Seniors: 46%)
Type 2 - Genital  (Freshmen: 0.4%      Seniors: 4%)
Types 1 & 2 found in genital lesions
Diagnosed by examination and cultures
Can be transmitted even without visible lesions
Herpes Simplex Virus (HSV)
Symptoms
Blisters or ulcers on genitalia
Tingling and burning
Fever
Body aches
Swollen glands
Recurrent episodes may be less severe
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Herpes Simplex Virus (HSV)
Management
Can be controlled but not cured
Acyclovir for primary outbreak and flares
Recurrent flares in 80% of infected individuals exacerbated by:
Stress
Heat
Menstruation
Trauma
Chlamydia
5% of college students infected
Frequent association with other STD’s
Symptoms
Often no symptoms
Women: discharge, painful urination, pain with sex, heavy and irregular menstrual periods
Men: discharge, epididymitis (painful scrotum)
Can cause PID and infertility
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Gonorrhea (GC)
Incidence highest among sexually active  15-19 year olds  (24 cases per 1000)
Often associated with other STDs
Symptoms
Often no symptoms
Women: discharge, painful urination, pain with sex, irregular menstrual periods
Men: discharge, epididymitis (painful scrotum)
Both:  throat and joint infections
Can cause PID and infertility
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Syphillis
Rates increasing among youth/young adults (recent decrease in Dallas County)
Progressive disease
Primary phase:  single genital chancre (ulcer), swollen lymph nodes
Secondary phase:  more sores, usually on genitals
Late phase:  involvement of multiple organs
Curable with antibiotics
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Other Ulcerative Diseases
Lymphogranuloma Venereum (LGV)
Granuloma Inguinal
Chancroid
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Vaginitis and Cervicitis
Symptoms:  discharge, lower abdominal pain, abnormal menstrual bleeding, pain with urination, frequent urination
Sexually transmitted: trichomonas, bacterial vaginosis, yeast
Non-sexually transmitted:  bacterial vaginosis, yeast, soap or spermicide allergies, perfumes, foreign bodies (e.g. forgotten tampons)
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Other Genital Disorders
Yeast infections (Candida Albicans)
Scabies
Pubic lice
Molluscom contagiosum
Tinea cruris (jock itch)
Folliculitis (infected hair follicles)
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Hepatitis B Virus (HBV)
More prevalent and contagious than HIV
Transmitted by sharing body fluids
Kissing, sexual contact, sharing razors, transfusions, sharing IV needles
40% no known contact
Symptoms:  fatigue, nausea, malaise, liver enlargement
10% have chronic disease and risk for liver failure
Texas laws require immunization for all students entering 8th grade and now for infants.
Hepatitis B Virus (HBV)
Vaccine
ACHA recommends all college students be vaccinated
Series of 3 immunizations, given several months apart
Available at SMU Student Health Center
Human Immunodeficiency Virus
Only latex condoms can decrease transmission of HIV
Dallas County Health Department offers free, anonymous testing at SMU Health Center
Every other Friday.
Call 8-2141 to obtain phone # to schedule an appointment directly with Aids Prevention Project (funded by Dallas County Health Department)
HIV and AIDS in the US (6/97)
Total AIDS cases :  612,078
Estimated HIV prevalence : 650,000-- 900,000
1 in 300 Americans infected with HIV
1 in 300 Americans (all ages)
1 in 160 males (adult/adolescent)
1 in 800 females (adult/adolescent)
HIV and AIDS:  The Present
AIDS is the second leading cause of death among persons aged 25-44 in the United States (as of 4/98)
Mean (average) time between infection and development of AIDS is 8 to11 years
Increasing in women, African Americans, and Latinos
HIV in College Students
Study of 16,863 students at 19 large universities and colleges, 1989 (CDC & ACHA)
0.2% (or 1 in 500) infected with HIV
Compare to rate of HIV infection in military recruits = 0.14%
HIV Prevention and Risk Reduction
Abstinence, Abstinence, Abstinence
Condoms
Latex (male or female)
Significantly reduce but do not eliminate risk
Avoid petroleum-based lubricants, many medicated vaginal creams, massage oils
Spermicide (Nonoxynol-9)
Presence of other STDs increases risk
HIV Testing
Seroconversion (time from infection to positive antibody status) takes generally 6 weeks to 6 months (most convert in 90 days)
Two-step method (Elisa, Western Blot)
AIDS Prevention Project (UTSW Medical School) offers free, anonymous testing at SMU Health Center (call 214-944-1050 to schedule)
The Good News
HIV education is increasing awareness of AIDS and other STDs
Studies show modest but significant decrease in recent sexual activity
Use of condoms is increasing
Research has brought new and better therapies for many STDs in recent years
Making Sex Safer
ABSTAIN from sexual intercourse until you are in a long-term, committed relationship
Experiment with non-sexual ways to express affection
Communicate with your partner about sex
Making Sex Safer
Use condoms and spermicide every time you have sex
Limit your number of partners (1x2x10=20)
Women:  get yearly Pap smears
Get checked regularly for STDs