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	Brent S. Sumerlin
	Associate Professor	Office:	307 Fondren Science
	Department of Chemistry	Phone:	(214) 768-8802
	Southern Methodist University	Fax:	(214) 768-4089
	PO Box 750314	e-mail:
	Dallas, TX 75275-0314
	| Research Group Site |

Education & Experience:

• Associate Professor, Southern Methodist University, 2009-

• Assistant Professor, Southern Methodist University, 2005-2009

• Visiting Assistant Professor, Carnegie Mellon University, 2003-2005

• Ph.D. University of Southern Mississippi, 2003

• B.S. North Carolina State University, 1998

Our interests reside at the interface of polymer, organic, and biochemistries with particular focus on fusing the fields to prepare novel materials with hybrid properties. We employ a variety of techniques to synthesize well-defined homopolymers, block copolymers, or polymer-protein conjugates with selected functionality, composition, and molecular architecture. These macromolecules demonstrate solution self-assembly tunable by changes in temperature, pH, or the concentration of a specific small molecule solute. Applying the appropriate stimulus can lead to assembly or disassembly of nanoscale aggregates (e.g., micelles, vesicles) or macroscopic materials (hydrogels). Many of our responsive polymeric materials are designed to be biocompatible or biodegradable and have potential applications in drug delivery, tissue engineering, and surface modification.

Selected Publications:

• Ming Li, Hongmei Li, Priyadarsi De, Brent S. Sumerlin “Thermoresponsive Block Copolymer-Protein Conjugates Prepared by Grafting-From via RAFT Polymerization“ Macromolecular Rapid Communications 2010, In press. [Link]

• Hongmei Li, Abhijeet P. Bapat, Ming Li, Brent S. Sumerlin "Protein conjugation of thermoresponsive amine-reactive polymers prepared by RAFT" Polymer Chemistry 2011, In press. [Link]

• Brent S. Sumerlin and Andrew P. Vogt "Macromolecular Engineering through Click Chemistry and Other Efficient Transformations" Macromolecules 2010, 43, 1-13. [Link]

• Debashish Roy, Jennifer N. Cambre, Brent S. Sumerlin "Future Perspectives and Recent Advances in Stimuli-Responsive Materials" Progress in Polymer Science 2010, 35, 278-301. [Link]

• Ming Li, Hongmei Li, Brent S. Sumerlin "Conjugation of RAFT-generated polymers to proteins by two consecutive thiol-ene reactions" Polymer Chemistry 2010, 1, 854-859. [Link]

• Debashish Roy, Aman Ullah, Brent S. Sumerlin "Rapid Block Copolymer Synthesis by Microwave-Assisted RAFT Polymerization" Macromolecules 2009, 42, 7701-7708. [Link]

• Priyadarsi De, Sudershan R. Gondi, Debashish Roy, Brent S. Sumerlin "Boronic Acid Terminated Polymers: Synthesis by RAFT and Subsequent Dynamic Covalent Self-Assembly" Macromolecules 2009, 42, 5614–5621. [Link]

• Debashish Roy, Jennifer N. Cambre, Brent S. Sumerlin "Triply-responsive boronic acid block copolymers: Solution self-assembly induced by changes in temperature, pH, or sugar concentration" Chemical Communications 2009, 2106-2108. [Link]

• Andrew P. Vogt, Brent S. Sumerlin "Temperature and redox responsive hydrogels from ABA triblock copolymers prepared by RAFT polymerization" Soft Matter 2009, 5, 2347-2351 [Link]

• Priyadarsi De, Ming Li, Sudershan R. Gondi, Brent S. Sumerlin "Temperature-Regulated Activity of Responsive Polymer-Protein Conjugates Prepared by Grafting-from via RAFT Polymerization" J. Am. Chem. Soc 2008, 130, 11288–11289. [Link]

• Andrew P. Vogt, Brent S. Sumerlin “Tuning the Temperature Response of Branched Poly(N-Isopropylacrylamide) Prepared by RAFT Polymerization” Macromolecules 2008, 41, 7368-7373. [Link]

• Debashish Roy, Jennifer M. Cambre, Brent S. Sumerlin "Sugar-Responsive Block Copolymers by Direct RAFT Polymerization of Unprotected Boronic Acid Monomers" Chem. Commun. 2008, 2477-2479. [Link]

• Ming Li, Priyadarsi De, Sudershan R. Gondi, Brent S. Sumerlin "Responsive Polymer-Protein Bioconjugates Prepared by RAFT Polymerization and Copper-Catalyzed Azide-Alkyne Click Chemistry" Macromol. Rapid Commun. 2008, 29, 1172-1176. [Link] Highlighted in the June 2008 edition of Materials View.

• Priyadarsi De, Sudershan R. Gondi, Brent S. Sumerlin "Folate-Conjugated Thermoresponsive Block Copolymers: Highly Efficient Conjugation and Solution Self-Assembly" Biomacromolecules 2008, 9, 1064-1070. [Link]

• Jennifer N. Cambre, Debashish Roy, Sudershan R. Gondi, Brent S. Sumerlin "Facile Strategy to Well-Defined Water-Soluble Boronic Acid (Co)polymers" J. Am. Chem. Soc. 2007, 129, 10348-10349. [Link]

Courses Taught:

• Organic Chemistry (CHEM 3371)

• Introduction to Polymer Chemistry (CHEM 5333)

• Overview of Materials Chemistry (CHEM 6118)